Malignant Hyperthermia (MH) is a rare, inherited musculoskeletal syndrome that presents as a hypermetabolic reaction triggered by exposure to volatile anesthetic gases (e.g., desflurane, enflurane, halothane, sevoflurane) or the depolarizing muscle relaxant, succinylcholine. The signs of MH include muscle rigidity, rapid heart rate, high body temperature, muscle breakdown and increased acid content.
CRNAs, student registered nurse anesthetists, other clinicians, and facility administrators are encouraged to review available resources and assess their knowledge, preparedness, and training to periodically affirm the team’s readiness for an MH crisis. Anesthesia professionals may be the first to recognize the onset of an MH crisis, but a coordinated team response is vital in the effective treatment and management of MH.
The Malignant Hyperthermia Association of the United States (MHAUS) has developed numerous resources and guidance for clinicians and patients to promote optimum care and scientific understanding of MH and related disorders. Debra R. Merritt, MSN, CRNA is a member of the MHAUS Board of Directors.
- Malignant Hyperthermia Crisis Policy Template (Login Required)
- Malignant Hyperthermia Crisis Preparedness and Treatment, Position Statement and Policy Considerations
- Malignant Hyperthermia Awareness and Training Month, AANA NewsBulletin, March 2016
Testing for MH
- Safe and Unsafe Anesthetics
- MH Susceptibility and Associated Conditions
- Stocking an MH Cart
- Preparation of Anesthesia Workstations to Anesthetize MH Susceptible Patients
- Preparation of the Drager Fabius Anesthesia Machine for the Malignant–Hyperthermia Susceptible Patient, Anesthesia & Analgesia, December 2008
- Emergency Treatment for an Acute MH Event
- FAQs - Management of MH-Susceptible Patients
- Current Concepts in the Management of Malignant Hyperthermia, Anesthesiology News, February 2014
- Creation of a Guide for the Transfer of Care of the Malignant Hyperthermia Patient from Ambulatory Surgery Centers to Receiving Hospital Facilities, Anesthesia & Analgesia, January 2012
The North American Malignant Hyperthermia Registry of MHAUS
The resources on this page may incorporate or summarize views, guidelines or recommendations of third parties. Such material is assembled and presented in good faith, but does not necessarily reflect the views of the AANA. Links to third-party websites are inserted for informational purposes and do not constitute endorsement of material at those sites, or any associated organization.